In a microwave-safe mug (at least 10 to 12 oz) add flour, protein powder, baking powder, brown sugar, and salt. Stir to combine.
Add milk, melted butter, and vanilla. Stir until completely smooth with no flour pockets.
In a small bowl mix brown sugar, cinnamon, flour, melted butter, and salt with a fork until crumbly. It should hold together when pressed but break apart easily.
Add half the batter to the mug. Sprinkle half the streusel over the batter. Pour the remaining batter on top. Finish with the remaining streusel.
Microwave on high for 45 seconds. Check. The top should look mostly set but still slightly soft in the center. Add 10-second increments as needed. Total time is usually 60 to 70 seconds. Do not overcook. Slightly underdone is the goal.
Let rest 60 seconds. Whisk glaze ingredients until smooth and drizzle over the top while still warm. Eat immediately.