Preheat oven to 375°F.
In a skillet, cook ground beef with diced onion, garlic powder, paprika, salt, and pepper until browned. Drain excess fat if needed.
In a greased 9x13 baking dish, combine uncooked pasta, cooked beef mixture, Greek yogurt, ketchup, mustard, 1 cup of shredded cheddar, and broth. Stir well to combine.
Cover tightly with foil and bake for 35–40 minutes, or until pasta is tender.
Uncover, sprinkle remaining 1 cup of cheese on top, and bake another 5–10 minutes until melted and bubbly.
Let cool slightly before serving.